I have HSV 1 and 2. I have been on Valcyclovir and taken Lysine and honestly, these didn't seem to help. The only thing that seemed to help is drinking a lot of water and the passage of time. I have never seen lesions, however when the symptoms come they are constant. My bottom lip stays itchy. After YEARS of daily itching, the itching finally went away - until I got lip fillers to enhance the fullness of my lips. The itching came back and it will not stop! I welcome any advice or comforting words.