kdogstew

My wife contracted about 2 years ago and she has had multiple OB since then. I recently convineced her the medicine would help and decrease her OB and cuase them to be shorter and easier. She had just had 2 OB back ro back that eneded about 14 days ago. Now she has 2 OB coming up at 2 different locations. I am desperately needing advise. Has anyone else had the pills cause them innitially and then they subsided later or do some people find the medicine make the OB much worse? I am so sad right now

Wow. I was greatly mistaken and confused. confused. This is for Herpes of the cornea only. I did read that this company is working on HSV2 also but I thought it was much closer. Im sorry to post this. I thought this was worthy to pass along. But now I feel silly.

Wait. I was correct. It is in phase 3 of human trials in China hospitals and has gained status as an "orphan drug" in the US via FDA. Also the second article says they already have started the work on HSV2. I think this is big news. But maybe I am wrong.

Mr Hopp. Can you explain what that term herparic stromal keratisus (I didnt get that out corrclectly). But can you help me understand what that means? Is this relevant to us? I know its HSV1 and not 2 but I think the research sort of helps toward a cure for both. What is thst term about? Is that the genus and species? I mean is this big news? I will check back in a week or 2 and see if you have any opnion of this. I am happy to send the full article if that would help

This article seems more optimistic than I am. But if just google BD111 this is fhe main one that sort of "pops up". It looks like legit science. But I am reluctant to just go "all in" on this. It seems like we would be hearing more about this state side. Just wanting others thoughts

I comoletely understand the reservation to get to eager about any possible cure but this article says it is in human trials (I fhink)? But I was wrong when I said phase 3 of human trials. But if does seem to say "human trials" not mice trials. Right? Just wondering if anyone had any additonal knowledge of this. I do agree though. Cant just sit around and wait for a cure. That is not healty at all

I was reading up on "cure update information" hoping to hear good news and ran across some interesting news out of China. Apparently they are working on gene editing drug to cure? Seems like having good results? Currently in phase 3 human trials? It is BD111. Does anyone know more about this? Is this legit or just more hype? Would love to hear any feedback. I have lost confidence in Fred Hutch research. Anyone done any reaearch on this China research?

I have only had one OB in my life HSV2 but I have had some annoying tingling from time to time. Nevertheless I am always hesitant to begin any meds that might bring on future OB. RingoQ says it can cause problems if you have current bacterial or viral infections. Normally I dont let HSV2 dictate other health measures but I do like to probe the forum just to see if anyone has had any issue or heard of any issue. Thanks in advance if anyone has any input.

I agree with Mr_Hopp about not putting your life on hold but I also think the cure has gone from "impossible" to a matter of time. When Fred Hutch got imvolved its gonna happen. They continue to provide research that indicates all obsticles are being resolved. It just takes so long for things to get done. When they fogured out how to transport restiction enzymes directly to the root ganglia and find the "hiding virus" that was ground breaking. Also realizing mega nucleases are better than crisper for cutting Herpes. I believe now they are working with guinea pigs which is good bc they have an immune system more similar to humans than mice. Keep the faith but realize its probably gonna be 10 more years before a cure is available for public. Hoping sooner but at least now we have hope.

To reply to my own post. I would like to offer just my personal opinion and I’m not a doctor but I teach an honors Biology course in a public high school. So this is just my opinion but I think I have some level of credibility. From what I see Herpes is “on the clock” and it’s days are numbered. Keith Jerome and his team are going to end this. Their meganucleases and vectors of transportation and “finding the virus while hidden in ganglion” is crazy impressive. People… just hold on. 20 years ago they said it was a hopeless cause and Herpes would never be cured. A lot has changed in 20 years. I hope this information gives someone some encouragement.

I try to keep up with the science concerning vaccines and or cures and I feel like I usually understand the science/verbiage fairly well but this has me stumped. Does anyone understand the impact of the human trials for this candidate? Would this potentially make for a full vaccine and prohibit transmission from an infected person to a non infected person? It seems the research was done in UK but human trials have started in LA California. I guess I’m suprised I can’t find more information about this. BTW. I do know this is NOT what the Jerome Project is doing. They are seeking a permanent cure. The RVx201 seems to be a potential vaccine but It is not clear to me if it will also be used to lesson symptoms or help an any other ways. Does anyone have any insights?

Yes it can absolutely bring on an OB. I had tested negative several times with IGG test. That actually should not happen but it did. I guess I had been infected years and years ago. My ex wife had it and I knew it so I chose her over the possibility of contracting. Even after we split up I had several IGG test. All negative. Then I had the vaccine and BAM. First and a horrible OB. It was back in Feb. of this year when this happened. Now I don't really have any symptoms (such as the horrible tingling and itching) but I sometimes feel like it affects my strength. Bottom line is YES if can bring one on!

I am positive for HSV2 and have only had one outbreak or at least one confirmed. However I have burning in my urethra from time to time. But I don’t have other “typical” symptoms associated with the burning. Like no blisters on the shaft, no tingling, no itching, no tightness in legs. But when I urinate it almost makes me cry. I’m going to GP tomorrow. This seems more likely to be UTI. But. Has anyone had ulcers in urethra and if so could you see them from opening the tip? Any advice would be appreciated.

I was completely unaware I had HSV2. I even had multiple IGG test confirming I was negative bc I had been married to a lady with it. So to my knowledge I was negative. I Had first vaccine shot and BAM a huge outbreak. I am still trying to adjust to the new normal but it is very difficult. I am absolutely confident that the vaccine brought on the outbreak. Keep in mind I’m not saying the vaccine gave me the HSV2 I guess I already had it but it did bring on my first outbreak and it was horribly bad. That was in Feb I have not had a follow up OB break lots of annoying tingling and pain down my leg off and on. That is my experience.