My period definitely does it, it's more itching but I get the pimple on the butt to lol. The way I can tell sometimes , and it's gross and I shouldn't touch them, is I put my finger on it and if it burns. Slightly. But look into the betadine. My friend who has it she uses it. She said that was all she needed. But my body is to stressed, with my bipolar and life I need meds. It'd you decide to use it put it on the first sign of outbreak it dries it up fast. Sometimes I feel so paranoid that every itch I have is it. You ever get like that?