Newlook2013
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Posts posted by Newlook2013
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@ Ladyf123, sounds like hpv to me( the tag + the dull ache....). I'm not a doctor though.
I would go back too or seek second opinion elsewhere.
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hmm.....@ bowersn84, so you can't find him or his mom anywhere anymore....?
SMH.....TTFW.
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@ Cecibuendia, as Dancer say in some other words, herpes rarely change our lives, its our attitude that often changes after herpes and we have the potential to direct our attitudes towards a positive course....and so an approved herpes vaccine will fail to change our lives if we could not hold/direct it now.
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sorry to anyone if I sounded "a bit arrogant" by that statement.
but, I had more of "Well, we DO have the potential for COMPLETE power over it right now" kind of thought when I actually said that.
I truly understand its not personal...and I genuinely appreciate that perspective. infact I don't even think there is anything good in taking things personal as I learnt after getting H.( my lesson?....well a girl I really loved and trusted dissapointed me and left me without explanation and did not even want me to talk about that, when I disclosed my job loss to her and I took things personal by "hitting on the road"-and met herpes :-* )
its also amazing how the things we say sometimes or most times have different perspectives with individuals...that's a wonderful thing I think bcos it kind of acts as an opportunity to double- check ones statements, not necessarily ones ideas.
For instance, one might feel that, the fact that many promising herpes research have failed over the years does not mean all will fail in the years to come. So one might "bite fingernails" when they hear a good friend say somethin along the lines...." I for one have heard of many promised "cures" for the last 35+ years and so far none have come to pass".....when in fact, all he/she is trying to tell me is not to hold my breath for a promised herpes "cure" and that I should move on with my life.
But its all beautiful....
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Humans are intelligent creatures (or are supposed to be) and we should have power over everything around us, including hsv. Thanks to this forum and everyone here as your support and encouragements greatly empower almost everyone to control their lives rather than letting a virus control/ define them.
Genuine Scientists also being humans, can not continue to fail in their efforts to effectively halt h. A number of hurdles have been overcome over the years through a number of failures......
It does not really help when we get soo obsessed with high hopes or promises of a cure in a specific time frame especially when things dont go as expected.
However, as it happens in solving any crossword puzzle, you can feel it and you can see it when you are getting closer to the solution...( infact at times, you could get very close to it but it could take much longer time than you expected).
So much to talk about until we get there.
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tmi lol received and being processed......
advice on obsession aknowledged as well....
Oh what a world and a feeling....
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Well iv tried doing some research on this but seems as still early to prove it. im not sure whether anyone has any further proof or information to show otherwise.
The question is how would a future licensed hsv2 vaccine perform against hsv1? or would there be the need for an hsv1 vaccine after an effective hsv2 vaccine?
my current thoughts are based on the current existing facts I state below as:
1. almost all existing medications eg: acv and valtrex developed for hsv2 seems to work for hsv1 as well. ( though there are reports of not working for either types, like I seem to have experienced with acyclovir and my hsv1 )
2. it seems all tested but failed hsv2 vaccines so far had some significant efficacy against hsv1 both theraputic and prophylactic wise. A good eg is the GSK's herpevac for hsv2 which failed for hsv2 but had approx 58% hsv1 theraputic efficacy and approx 73-74% hsv1 prophylactic efficacy( in negetive women)
as per below link.
http://bvsalud.org/portal/resource/en/mdl-22216840
Thus, I am thinking that though hsv1 vaccine would not be difficult to make after an effective hsv2 vaccine, there might not be the need for it.
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yea, I agree with Dancer. If that happens( which is more possible than autoinoculation which lessens with increasing antibodies), you may or may not see the effect.
Also, my thoughts in the event of seeing the effect are: gh1 person would likely see the effect more than would a gh2 person on their genitals. The reverse scenario could likely also occur orally.
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deleted.
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@whitedaisies,
"maybe" its bcos the chickenpox virus is known to go dormant for a loooong time after initial outbreak unlike hsv. hence, maybe the antibodies to the chickenpox might want to go to sleep for a while...but a chickenpox vaccine might not allow the antibodies to sleep.....just maybe.
I just pasted below qstn and answer from Bill Hayford's( a microbiology prof) scienceblog which is quite relative to the discussion...... "http://herpesvaccine.scienceblog.com/2013/06/15/purpose-of-the-herpes-vaccine-blog/"
Peter: September 8, 2013 at 2:07 pm #
Hi Bill
Perhaps you could clarify a few points on the differences between EBV, HSV1 and
Shingles etc. Reason for query…I have suffered from HSV1 since childhood and it is affecting pain in my eyes, ears and scalp. Four years ago I received the shingles vaccine and like magic my
outbreaks ceased. They have just started again, this time with underarm swelling
and am wondering whether my response
to the shingles vaccine is anecdotal?
Also, would a second dose of shingles vaccine have any harmful effects?
Merck does not have research data to
support top-up.
REPLY
Bill Halford: September 15, 2013 at 10:57 am#
Hi Peter,
Please forgive the delayed response.
I have been up to my eyeballs with medical school teaching responsibilities.
At the bottom of this post, I will cut-and-
paste and a paragraph from a book chapter I wrote two years ago that clarifies the relationship between EBV,
HSV-1, and shingles…..the bottom line
you need to know for now is that these are 3 of the 8 known human herpesviruses. The next thing you need to
know is that Epstein-Barr Virus,cytomegalovirus, and HHV-6, HHV-7,
and HHV-8 live in blood cells (macrophage, B cells, or T cells), and
thus really don’t have much to do with
herpes simplex virus 1 and 2 beyond
sharing a common evolutionary
ancestry….dinosaurs would have had
herpesviruses…..they have been around
for eons…..today they are found in fish,
crocodiles, seals, kangaroos, oysters.
Collectively, there are more than 130
known herpesviruses, and 8 of them infect humans. So, now having addressed
all of the irrelevant viruses above that
bear the word “herpesvirus” in their name,
we come to three human viruses that
are close relatives: HSV-1, HSV-2,
and VZV. HSV-1 and HSV-2 are, as you
know, incredibly similar viruses. Varicella-zoster virus(VZV) is also a very
similar virus, and shares at least 50
(if not 60) genes in common with HSV-1
and HSV-2. To put a ballpark number on
it, VZV is 25–50% similar to HSV-1,
whereas HSV-2 is ~98% similar to HSV-1.
Elsewhere in this blog, I refer to a French study that reported something
comparable to what you describe above:
http://www.dovepress.com/efficacy-of-the-anti-vzv-anti-hsv3-vaccine-in-hsv1-
and-hsv2-recurrent–peer-reviewed-
article-OAJCT-MVP
The short answer to your question is that,
“No it would not hurt you to get another
shingles vaccine.”
The difference between the “chickenpox
vaccine” and the “shingles vaccine” is
that the shingles vaccine contains a 13-
fold higher concentration of live-attenuated VZV Oka strain virus in each
shot. So, if this approach is going to
work, it would make sense that the
shingles vaccine would be better than
the chickenpox vacccine (because there
is 13x more virus available to engage
your immune system).
Regarding why it might work is that
VZV and HSV-2 share a lot of viral
proteins in common.
The reality is that this is how we stopped
the spread of the human disease smallpox……we immunized people with
a similar,but distinct virus, originally
isolated from the cowpox lesions that
cows get on their udders. This “cowpox
virus” was not identical to the “smallpox
virus,” but they had enough in common
that the cowpox vaccination elicited an
immune response that CROSS-PROTECTED against its close cousin the
smallpox virus.
The cowpox virus was first isolated by
Edward Jenner in the 1790s, and he
published a paper in 1798 reporting the cross-
protection against the deadly smallpox virus
(which killed 25% of Europe’s population on
more than one occasion).
After 1798, the virus was passed from
vaccine recipient to vaccine recipient
who developed a pock lesion at the site
of vaccination that was loaded with
the vaccine virus. Eventually, the virus
came to be known as the “vaccinia virus,”
and this is precisely the origination of
the term “vaccination.” Originally, the
term was introduced in contrast to the
term “variolation.” Variolation meant
to deliberately inoculate people with the
virus that caused smallpox (i.e., the
variola virus). Variolation did protect people against smallpox, but 1-2% of
people variolated developed smallpox
disease and died. In contrast “vaccination” was a much safer
alternative and yet still elicited
protection against smallpox.
Louis Pasteur developed a “rabies
vaccine” in the late 1800s,and so named the procedure in honor of Jenner’s
discovery of the “vaccination” procedure
to prevent smallpox. Hence, Louis Pasteur (nearly 100 years later) gave us
the modern meaning of vaccination,
which means “injecting someone with
a benign substance that is antigenically
related to a disease-causing microbe in
order to elicit an immune response that
is CROSS-PROTECTIVE against the
disease-causing microbe.” I digress.
The relevant point is that we cured
smallpox with a SIMILAR, BUT DISTINCT
vaccinia virus that was derived from
cowpox. Likewise, many countries use
the BCG vaccine to reduce the incidence
of tuberculosis caused by Mycobacterium. tuberculosis.
The active ingredient in the BCG vaccine
is a related bacterium known as
Mycobacterium bovis…..SIMILAR,
BUT DISTINCT from the agent of
tuberculosis.
So Peter, yes, there is a historical
precedent for the phenomenon you
describe of using VZV which is SIMILAR,
BUT DISTINCT from HSV-1 in order to
elicit an immune response that is CROSS-
PROTECTIVE. against diseases caused by HSV-1. If this is true, I note that a
live- attenuated HSV-1 vaccine would
be more effective as a therapeutic
vaccine, as there would be 99.9%
similarity to your HSV-1 virus as
opposed to the 25-50% similarity of
the. VZV vaccine.
However, the difference is that you can
get a shingles vaccine today, whereas
a live- attenuated HSV-1 vaccine is
still far off on the horizon. I would not
necessarily predict that VZV vaccination
would be CROSS- PROTECTIVE against
HSV-1 or HSV-2, but if it works, then
who am I to knock success? Thanks for
the interesting query.
–
Bill H.
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@ Dancer, positivelyBeautiful and inka: Soo powerful and true.....
@CityofAngels: you tried to be honest with ur view from the other side of life.
its really a delicate issue but I believe its ok if u approach things with honesty( not the lies that tries to make someone feel good) while u make vary sure that the other person finally understand ur decision without getting hurt.
life is indeed complex and full of uncertainties and there is risk in everything we do.
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"@ dancer, ok this is something ive
been curious about since learning my
status. so, if a cure were ever to be
found, a person would eventually test
with an igg test as negative cause
the antibodies would be gone? I
thought our bodies keep a "blueprint"
around for similar diseases?"
would depend on the type of "cure". if its a tamed live virus or DNA type( which are both not expected to clear everything and would also remain in the body while continuing to stimulate immunity as hypothesized ), then we would still show the " blueprint". however, anything that can enter them camp and kick em all in e ass, then itself enter that hot boiling soup as in the terminator 2, could just result in a clean sheet with time.
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Ok, a delicate correction in my earlier
statement, " I read that it has a lot to
do with healing times of OBs."
I should rather have put it, "I
presume that it has a lot to do with
healing times of OBs"
But the point on blood types and
antigens/immune responds to
infections are real scientific findings.
I personally find that a bit abstract as
I really don't get sick too( well, I
usually make lifestyle changes
immediately I find somthn wrong with
my health even before I got herpes-
though herpes has added a lot more
and a great value to that )
On the whole, I think that finding
holds true esp when we don't
maintain a healthy lifestyle (and/or
diet for our body) for
sometime..there, our blood (AB) type
though in a class of its own could be
doing just what has been theorized.
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thanks Dancer....
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the little I know about Ebola tells me that, Ebola belong to quite a different family of viruses called filo ( not sure how its spelt) virus, and they behave quite differently and their structure too is different altogether from herpes family.
However, though HIV too behave differently, they have some similarities with hsv1 on their surface antigens.( one evidence is why acyclovir/drugs meant to prevent replication of herpes virus seem to help HIV sufferers and vice versa.
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I read that it has a lot to do with healing times of OBs.
Technically, AB blood types( + and -) has no antibodies( where we hav both B and T cells to fight infections I guess) in their plasma since the effect of their A antibodies neutralises the effect of their B antibodies. So in a sense, though they are not immunocompramised, AB people do not aggressively fight off infections unless of course they are properly primed.
O blood types has the strongest antibodies as they hav both antibodies of A and B.
Also, yes I read that herpes virus does not stay in the blood but in our cells/nerves/tissue, so it should not be transmitted through transfusion.( but an hsv negative person would get the antibodies for herpes by receiving blood from an hsv+ person, nevertheless, that may not offer a complete protection from future exposure, since a lot of other factors like specific strain of virus, the virus possible clever mutations etc would come in)
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I'm tempted to believe that most often, first herpes infection does not come alone but with other infections ( eg: yeast, bacteria, mullescom contagiosum etc). But with time( say 2 yrs after) the ones that can't hide are cleared leaving only the stupid coward herpes virus.
Apart from the occasional creeping and/tingling sensation with some rashes (and never a sore, usually lasting between 3 - 4 weeks) I get down there ( which has greately receded after first 6 months), I have had atleast some other 1, 2, and/or 3 bumps each at different places (one on my right inner wrist which I believe to be autoinoculated by scratching my balls during sleep and this looks more like mullescum to me than herpes bcos it turned unusually dark with a central core that fell off and just about healing after being there for about 4 months , the other two at the base of my penis in a similar position as urs, also being there for about 6 months, gone now but left some tiny 2 close by, not very visible unless I shave) which looks totally different from the rashes I considered as hsv1 rash.
Iv also had some isolated number of rashes at my back near the spine which have been taking about 3 weeks to dissapear...almost being cleared at the moment.
Actually, I am not really doubting my ghsv1 test confirmation but the other wiered looking bumps makes me wonder.....
I tested for all the standard std without herpes & HPV 3 months after my exposure ( in Sept 2013) and was negetive for all. Then after 5 months when an sti docter diagnosed a lesion in my tigh to be herpes, I went for both igm and igg test. The igm was negetive for both 1 and 2 but the igg came back positive for hsv1.
I have taken 3 full coarse of oral acyclovir after my diagnosis in February ( I honestly did not see any difference it made and don't remember any side effect) and have not taken any anivirals sine June.
I'm AB+ blood type sometimes making me think why my lesion take a while before clearing or probably why I don't seem to be completely free of any rash or bump at any point ( though I see a great reduction in number and frequency now with those at my genitals almost not reccurring )
hopefully I would go for another test on everything again somewhere next year.
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....not ignoring the quite number of drugs and vaccines in the FDA's pipelines at a very slow pace.
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I think the FDA won't clear them cos either the makers have not shown that their drugs or treatments are safe and efficient than the existing valtrex, acyclovir and the like or are simply not doing enough to show proof of a real deal - even in their own country....and that will surely keep em in the closet.( I can't give a lot of examples bt I think I read about Ozone therapy in Cuba and Lupidon G, H vaccine in Europe )
I recon that if someone somewhere is able to hit the world market with smthn backed by real trial data and scientific proof of concept, it would kick whatever big pharma has defended for so long a time out of business and they would surely want to bring in new ideas.....that would be the competetion that could bring out the best and leave out the mediocres.
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I can imagine how a number of herpes stuffs would be approved by the FDA should any different country unveil just a single one.
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Hi Sidney, it ws after my diagnosis and subsequent test confirmation that I tried to look for support and that was how I found this forum.( althought I googled a bit when I got my first rash, bcos I had no idear what was going on)
A lot of people including you ( SS) came here bcos you didn't know what to do or didn't know what was going on...and you were advised to do "what u finally did".
No one came here for diagnosis.
and no one here diagnosed u with hsv2 on your chin.
I just copied what u said in ur second post ( @ Don't Let this Happen to You!) below:
" Thanks for caring. I have been
diagnosed with HSV2 on my chin"
I love u Sidney.
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well said....
to me, the fact that I got herpes just plainly convinced me that ther is God.( im not inferring that herpes is my punishment for what iv done in de past...far frm dat....if it is, hell yea, I would be excited cos I have the chance to make the most of it. unlike a dude who would jump into a trusted friend's car only to be crushed to death or somthn and never have a second chance to move on)...and I can only talk about herpes cos dat is what I am dealing with.
I realised ( initial couple of months) after my diagnose that, although I heard abt herpes, I never thought I could get one and even doubted its estimated percentages of infection given by dr's/ statisticians. Now here is the "reality" written in my ganglia.
with that, I convinced my self dat, no matter any doubt in my mind, there is a God who created everything( or mother nature for dat matter) despite de fact dat I don't have eyes to see him or the hsv virus either.
"I've come to doubt the bible being a true
account of actual history".....
well those that wrote de bible I remember added dat God guided dem to write whatever they wrote. As to de versions existing today, I can't say much on that but I think if God thinks any account is inaccurate, he would do something abt it.
again, I feel dat a lot will be up to us to find the reality/truth for ourselves when we seem to hav sm doubts about any account of it.
"why would god do this to me?" Or "god will find us a cure..."
what I hav observed is dat, any miracle that I read/hear God did in the bible were in my view done to either prove his point or directed to make his purpose happen.
and some of them were not done instantly. ( haha I can't remember any quote now, bt yea I think de Israelites went into exile for about 70 years before they were guided back home)
long story hur?
I also read that humans hav been searching for a herpes cure for about 60yrs now.
in any case I also found that its approximately 6040 yrs in 2014 since de first human walked de earth....well so if God has not involved himself in our day to day lives( such as the search for herpes cure) as we perceive even though we can't confirm the reality, and he has not killed any scientist who is daring ( or perhaps seized their apparatus),...
I don't think I can blame him for dat or think he is late in finding us a cure for herpes in 60 yrs or so.
I might have gone wayward on the point, but I personally feel that, our thoughts, doubts and perceptions on herpes cure or Gods intervention/existence might be quite different from the reality and they are definitely not capturing every deteil in the scene.( as we can only talk about evidences and data available to us which is different frm how a spirit being does things)
So as has been said ( and I agree) " pray as evthing is in Gods hands but Act as though they are in your hands" He can/will intervene in his own time.( and infact for every other worries).
cheers.
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:-) :-) :-).......:'(:'(:'(
:-);-);-):-)
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good point...I will call it "defensive driving."
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Skin Tag- Need your feedback ladies
in General herpes discussion
Posted
I would be a bad doctor then.
cheers...;-)